Any superheroes that take the law of equal and opposite reaction seriously? Like, you can imagine people being very strong, and I suppose you'd also have to assume various body parts could take extreme pressure, but you still need to support the weight you carry with something, and superhuman inertia doesn't really make sense.
@ianbicking saw a fun exploration once of whether Superman's powers could be explained by an ability to arbitrarily change the mass of things without changing their velocity. So it's not that he's very strong but just that he can make things light so he can pick them up or throw them or whatever. Not in keeping with canon of course
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